Paroxetine is an antidepressant that belongs to a group of medicines called selective serotonin reuptake inhibitors (SSRIs). Paroxetine works by increasing levels of serotonin, which helps reduce symptoms of depression and improves mood, anxiety, and other disorders. Paroxetine is used to treat depression, obsessive-compulsive disorder (OCD), panic disorder, generalized anxiety disorder (GAD), social anxiety disorder (also known as social phobia), premenstrual dysphoric disorder (PMDD), and posttraumatic stress disorder (PTSD). Paroxetine is in a class of medications called selective serotonin-reuptake inhibitors (SSRIs). It treats depression and other mental illnesses by increasing the amount of serotonin, a natural substance in the brain that helps maintain mental balance. Detailed Paroxetine dosage information for adults and the elderly. Includes dosages for Depression, Major Depressive Disorder, Panic Disorder and more; plus renal, liver and dialysis adjustments. Paroxetine is used to treat depression, panic attacks, anxiety disorders, and a severe form of premenstrual syndrome (premenstrual dysphoric disorder). Learn about side effects, dosages, drug interactions, and more. Paroxetine is primarily used to treat major depressive disorder, obsessive–compulsive disorder, post-traumatic stress disorder, social anxiety disorder, and panic disorder. It is also occasionally used for agoraphobia, generalized anxiety disorder, premenstrual dysphoric disorder, and menopausal hot flashes. [16][17][18][19][20] Find patient medical information for Paroxetine (Paxil) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings.